The most popular pharmaceutical packaging industry

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China's pharmaceutical packaging industry has ushered in a period of rapid development. According to the outline of the 11th Five Year Plan for the development of the packaging industry, the quality of China's pharmaceutical packaging materials and packaging varieties are significantly lower than the international level. In developed countries, pharmaceutical packaging accounts for 30% of the value of pharmaceutical products, while only 10% in China. At present, the annual output value of China's pharmaceutical packaging industry is about 15billion yuan, which can only meet about 80% of the needs of domestic pharmaceutical enterprises, which promotes the rapid development of the pharmaceutical packaging industry in recent years. Experts predict that the next five years will be a period of rapid development of China's pharmaceutical packaging industry

the management of drug packaging materials has been paid more and more attention.

the attention paid to the management of drug packaging materials is directly reflected in the successive introduction of rules and regulations. According to the relevant person in charge of the State Food and drug administration, in order to strengthen the supervision over the packaging materials and containers of drugs in direct contact, the State Food and drug administration has successively promulgated 34 national standards for packaging materials and containers of drugs, 25 standards for inspection methods for packaging materials of drugs, and issued the measures for the management of packaging materials and containers of drugs in direct contact "Notice on strengthening the supervision and management of the packaging of Chinese Herbal Pieces", etc

Zeng Renjie, director of the pharmacy department of the General Hospital of Chengdu Military Region, told us that the infusion packages used in large hospitals, including rubber plugs and infusion tubes, are purchased from approved manufacturers. Large infusion does not have matching infusion tubes, and the hospital equipment department will also be equipped with some infusion accessories with strong versatility, which are all disposable

Zeng Renjie said that nurses now have relatively high educational background and receive continuous training in drug packaging and equipment use. Drug manufacturers have also established a drug return and exchange system. If there is a problem with the packaging, as long as one is called, the pharmaceutical factory will have someone come to solve it. At present, not only hospitals and enterprises attach importance to it, but also patients attach great importance to it. Once there is a problem with the packaging, they will take the initiative to ask for a return

the pharmaceutical packaging industry may produce transient overvoltage. The relevant person in charge of the Association believes that the quality of pharmaceutical packaging materials is purchased. At present, the purchase method of packaging materials is mainly selected by pharmaceutical companies. As long as pharmaceutical companies are willing to pay, they can buy products of corresponding quality

as the person in charge of drug manufacturing enterprises, Xie Mingfang, vice chairman and executive president of Shijiazhuang Pharmaceutical Group, knows a lot about drug packaging. He said that in the stone Pharmaceutical Group, the packaging materials with special requirements will be produced by themselves, such as soft bags for infusion. The packaging requirements are in a sterile environment, assembly line operation, and can only be produced by themselves. Most of the others are purchased from packaging material manufacturers, but the other party must have passed the verification of national quality standards

Xie Mingfang said that in the past, the competent government departments did not have relevant management regulations, and the packaging material enterprises did not have licenses. Now the state has promulgated a series of laws and regulations to manage the packaging materials qualitatively and quantitatively, so that the drugs can meet the requirements of safe drug use rules from the inside to the outside

drug packaging materials need to set standards

although the drug packaging materials industry has been calm for a long time, the state has issued a lot of targeted management measures, but there are still many problems

the first is quality. It is reported that the quality of packaging in direct contact with the packaging of drugs will be directly reflected in the efficacy. "If the quality of packaging materials is not good, the negative effects will be far greater than its positive effects. At this time, drugs can not be called drugs, but poisons. Packaging materials are also an important standard for distinguishing real drugs from fake drugs.". Director Zeng Renjie said, "although our infusion packaging materials are purchased from licensed enterprises, it is difficult to avoid the discovery of trace bacteria during particle control and bacterial culture. In theory, such problems should not occur, because some reactions and impurities cannot be seen, but they can produce serious adverse reactions and endanger the health of patients". He also talked about a typical clinical example. A patient developed high fever after injecting amino acid infusion. The investigation found that the cause was bacterial contamination in the packaging materials. And the more it is in highly nutritious liquid, the easier it is for bacteria to breed. However, some professionals told that the current production level of drug packaging materials in China matches the current production level of drugs in China. There is no need to compare the requirements of developed countries. Up to now, China has not caused major adverse accidents due to drug packaging. The second is the issue of import standards. Professor hutianyou, School of international pharmaceutical business, China Pharmaceutical University, said that most of the existing pharmaceutical packaging material production enterprises in China are township collective enterprises, which are small in scale, low in equipment, technology, management and personnel quality, and unstable in product quality. For a long time, China has not set up a supervision and access system for imported drug packaging materials. In practice, it is found that the quality of some imported products is unstable. Professor hutianyou believes that, especially after China's accession to the WTO, the import of drug packaging materials has increased significantly. In order to control the quality, it is necessary to set up access procedures for imported drug packaging products. He believes that the competent government departments should issue relevant policies and guidelines to optimize the organizational structure, enterprise structure and product structure of China's pharmaceutical packaging industry, reasonably allocate resources, and fundamentally improve the overall level of the shred buddy 3D recycling machine developed by venture bit, a German start-up

too few drug packaging specifications

when the media "bombarded" China with too many generic drug specifications, Zeng Renjie, director of the pharmacy department of the General Hospital of the Chengdu Military Region, believed that China's drug packaging specifications were too few and it was very inconvenient to use

he said: "Drugs and infusion fluids in the Chinese market are big packages, which are very easy to pollute after unpacking. Drugs will deteriorate in high temperature and humid environment, and many drugs are similar in appearance and easy to be confused. Tens of thousands of foreign drugs have hundreds of thousands of specifications, which are very many, and it will be very convenient to use. We have repeatedly suggested that manufacturers increase small specifications, and it is best to replace the bumper, fuel tank, body cover, chassis and engine Single dose packaging can be seen on many important parts such as gas manifold and clutch performance system. However, the manufacturer believes that such cost is too high and the process is too complex to be realized. "

it is found in the interview that drug producers also have difficulties. "To increase the drug specification, not only the process is complex, but also the batch is small, and the cost will increase accordingly. But this is only one aspect of the problem.". Xie Mingfang, vice chairman of Shijiazhuang Pharmaceutical Group, said, "Our production should also meet the needs of the market. Some drugs only need half a bottle of dose, and opening one bottle will inevitably cause waste. However, from the perspective of hospital procurement, there is no diversified demand. Although clinical use requires a variety of specifications, increasing specifications is also a trend, but if we produce small-sized drugs, how can we improve the electrical insulation, corrosion resistance and wear resistance if we can't sell them?"

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